CAS number：871307-18-5 molecular formula：C21H14ClFN6
Tpl2 Kinase Inhibitor 1 是一种选择性 Tpl2 抑制剂 (IC50=50 nM)。Tpl2 包括 COT 激酶和 MAP3K8，Tpl2 Kinase Inhibitor 1 可用于炎症反应和某些癌症的研究。 Tpl2 Kinase Inhibitor 1 is a 3-pyridylmethylamino analog, and is a selective Tpl2 inhibitor (IC50=50 nM). Tpl2 consists of COT kinase and MAP3K8. Tpl2 Kinase Inhibitor 1 plays an important role in the regulation of the inflammatory response and the progression of some cancers.
| Chinese alias | 4-[(3-氯-4-氟苯基)氨基] -6-[(3-吡啶基甲基)氨基] -1,7-萘啶-3-甲腈 | ||
| English alias | DTXSID20946032 | 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | Tpl2-IN-2p | K00599a | 4-(3-Chloro-4-fluorophenyla | ||
| CAS number | 871307-18-5 | molecular formula | C21H14ClFN6 |
| molecular weight | 404.83 g/mol | Exact mass | - |
| PSA | 86.500 Ų | logp | 4.400 |
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