compound introduction
Bafetinib (INNO-406, NS-187) 是一种有效的，选择性的，双重Bcr-Abl/Lyn双重抑制剂，无细胞试验中IC50为5.8 nM/19 nM，对T315I突变型的磷酸化没有抑制作用，对PDGFR和c-Kit的作用效果较弱。Lyn-IN-1 (Bafetinib analog) 是高活性 Bcr-Abl 和 Lyn 双重抑制剂。
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Bafetinib
CAS number：887650-05-7 molecular formula：C30H31F3N8O
overview
Specs
| Chinese alias | - | ||
| English alias | Lyn-IN-1 | ||
| CAS number | 887650-05-7 | molecular formula | C30H31F3N8O |
| molecular weight | 576.62 g/mol | Exact mass | ≥98% |
| PSA | 99.200 Ų | logp | 4.1 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
