compound introduction
一种腺苷衍生物，是腺苷-2':3'-环单磷酸的代谢产物。它通过一组依赖金属的磷酸二酯酶水解 2',3'-cAMP而生成。值得注意的是，2'-AMP 对肾小球前叶血管平滑肌细胞和肾小球系膜细胞的增殖具有抑制作用。这种抑制作用是通过 2'-AMP 和 3'-AMP 激活 A2B 受体实现的。 应用： 3′-单磷酸腺苷（3′-AMP）和2′-单磷酸腺苷（2′-AMP）是由金属依赖性磷酸二酯酶家族水解2′,3′-cAMP产生的代谢产物。2′-AMP和3′-AMP通过A2B受体抑制肾小球前血管平滑肌细胞和肾小球系膜细胞的增殖。 A derivative of adenosine, which is a metabolite of adenosine-2 ': 3' - cyclic monophosphate. It is generated through the hydrolysis of 2 ', 3' - cAMP by a group of metal dependent phosphodiesterases. It is worth noting that 2 '- AMP has an inhibitory effect on the proliferation of smooth muscle cells and mesangial cells in the anterior lobe of the glomerulus. This inhibitory effect is achieved through the activation of A2B receptors by 2 '- AMP and 3' - AMP.
