CAS number：182004-65-5 molecular formula：C16H17N3O3S·CH4O3S
KB-R7943 mesylate 是一种 Na+/Ca2+ 交换体 (NCXrev) 反向抑制剂，IC50 为 5.7±2.1 μM。KB-R7943 mesylate 通过激活JNK通路和抑制自噬通量来诱导癌细胞死亡. KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM. KB-R7943 mesylate induces cancer cell death via activating the JNK pathway and blocking autophagic flux.
| Chinese alias | 2- [4-[(4-硝基苯基)甲氧基]苯基]乙酯,甲磺酸酯(1：1), 氨基甲硫基酸 | S-[4-[(4-硝基苄基)氧代]苯乙基]异硫脲甲磺酸盐 KB-R 7943 | 硫代氨基亚胺酸4-[(4-硝基苄基)氧基]苯乙酯甲磺酸盐 | S-[4-[(4-硝基苄基)氧基]苯乙基]异硫脲甲磺酸盐 | ||
| English alias | GTPL4232 | HY-15415 | s4643 | 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE | 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea mesylate | C17H21N3O6S2 | methanesulfonic acid;2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate | A1 | ||
| CAS number | 182004-65-5 | molecular formula | C16H17N3O3S·CH4O3S |
| molecular weight | 427.49 g/mol | Exact mass | 10mM in DMSO |
| PSA | 193.000 Ų | logp | - |
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