Corynoxine 是一种从 Uncaria macrophylla 中分离出的四环羟吲哚生物碱。Corynoxine 是一种天然的自噬增强剂,可通过 Akt/mTOR 途径促进 α-突触核蛋白的清除。 Corynoxine is an enantiomer of Corynoxine B; induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
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Corynoxine
Dangerous GoodsCAS number:6877-32-3 molecular formula:C22H28N2O4
overview
compound introduction
Specs
| Chinese alias | 棒状菌素 | ||
| English alias | CHEBI:70072 | CCG-268458 | Corynoxine | 1443767-78-9 | AC-34387 | AKOS032948990 | AS-78371 | (E)-methyl 2-((1'S,6'S,7'S,8a'S)-6'-ethyl-2-oxo-3',5',6',7',8',8a'-hexahydro-2'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate | HY-N0901 | BDBM50566312 | ||
| CAS number | 6877-32-3 | molecular formula | C22H28N2O4 |
| molecular weight | 384.47 g/mol | Exact mass | 10mM in DMSO |
| PSA | 67.900 Ų | logp | 2.300 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H300: 吞咽致命
Statement of Preventive Measures:
P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。
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