CAS number：127191-97-3 molecular formula：C38H35N5O6S2
KN-62是可渗透入细胞的CaM激酶II抑制剂，IC50为0.9 μM，直接与该酶的钙调蛋白结合位点结合，同时还是非竞争性P2X7受体拮抗剂，IC50为15 nM。A potent and selective inhibitor of CaMKII KN-62 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.9 μM. A potent and selective inhibitor of CaMKII
| Chinese alias | - | ||
| English alias | KN62 | KN-62 | MFCD00083180 | NCGC00162398-03 | [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl] isoquinoline-5-sulfonate. | Ponceau BNA | [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-pheny | ||
| CAS number | 127191-97-3 | molecular formula | C38H35N5O6S2 |
| molecular weight | 721.84 g/mol | Exact mass | - |
| PSA | 147.000 Ų | logp | 5.600 |
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