CAS number：139298-40-1 molecular formula：C26H29ClN2O4S
KN-93是钙离子/钙调蛋白依赖激酶II（CaMKII）抑制剂，能竞争性阻断钙调蛋白与对应激酶的结合，Ki为370 nM。An effective inhibitor of CaMKII phosphorylating activity KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). An effective inhibitor of CaMKII phosphorylating activity
| Chinese alias | - | ||
| English alias | AMY3402 | (2-[N -(2-hydroxyethyl)]-N -(4-methoxybenzenesulfonyl)]amino-N -(4-chlorocinnamyl)-N -methylbenzylamine) | AKOS015994570 | BCP9000817 | J-007263 | NCGC00162399-02 | SCHEMBL14569460 | N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}me | ||
| CAS number | 139298-40-1 | molecular formula | C26H29ClN2O4S |
| molecular weight | 501.0 | Exact mass | - |
| PSA | 78.5 | logp | 4.5 |
| CAS | 139298-40-1 |
| HMDB ID | HMDB0253810 |
| ChEMBL ID | CHEMBL3199731 |
| PubChem CID | 3837 |
| DSSTox Substance ID | DTXSID401025982 |
| 生态与环境部编号 | _25Q1B45HG |
| PubChem Reference Collection SID | 518182248 |
| XLogP3 | XLogP3-AA: 4.5 |
| 复杂性 | 713 |
| Exact Mass | 500.1536563 |
| 形式电荷 | 0 |
| 重原子计数 | 34 |
| Molecular Weight | 501.0 |
| Monoisotopic Mass | 500.1536563 |
| 可旋转键计数 | 11 |
| 氢键供体计数 | 1 |
| 氢键受体计数 | 6 |
| 共价键单元计数 | 1 |
| 同位素原子计数 | 0 |
| 拓扑极性表面积 | 78.5 Ų |
| 定义键立体中心计数 | 0 |
| 定义原子立体中心计数 | 0 |
| 未定义键立体中心计数 | 1 |
| 未定义原子手性中心计数 | 0 |
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