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ARV-110

Dangerous Goods

CAS number：2222112-77-6    molecular formula：C41H43ClFN9O6

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physicochemical properties
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overview

compound introduction

Information ARV-110 ARV-110 is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR. ARV-110 completely degrades androgen receptor (AR) in all cell lines tested with DC50 of Targets AR (Cell-free assay) 1 nM(DC50)

Specs

Chinese alias-
English aliasBavdegalutamide [INN] | H6NYM0V650 | 2222112-77-6 | Bavdegalutamide [USAN:INN] | HY-138641 | N-((1R,4R)-4-(3-Chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)piperazin-1-yl)methyl)pipe
CAS number2222112-77-6molecular formulaC41H43ClFN9O6
molecular weight812.29 g/molExact mass-
PSA181.000 Ųlogp3.900

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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