m-PEG-NHS ester (MW 5000) 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子 The m-PEG-NHS ester (MW 5000) is a PROTAC linker belonging to the PEG class. It can be used to synthesize PROTAC molecules m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Appearance:Solid IC50& Target:PEGs Alkyl/ether In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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m-PEG-NHS ester
Dangerous GoodsCAS number:92451-01-9 molecular formula:(C2H4O)nC7H9NO5
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compound introduction
Specs
| Chinese alias | 甲氧基聚乙二醇 5,000 乙酸 N-琥珀酰亚胺基酯 | ||
| English alias | Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000) | ||
| CAS number | 92451-01-9 | molecular formula | (C2H4O)nC7H9NO5 |
| molecular weight | 293.27 g/mol | Exact mass | MW5000 |
| PSA | - | logp | - |
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Safety information
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
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