Salirasib是一种有效的竞争性prenylated protein methyltransferase (PPMTase)抑制剂, Ki为2.6 μM,其抑制Ras甲基化。Phase 2。 Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2.
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Salirasib
Dangerous GoodsCAS number:162520-00-5 molecular formula:C22H30O2S
overview
compound introduction
Specs
| Chinese alias | 沙利西布 | ||
| English alias | 1-ammonionaphthalen-2-olate | 2-(3,7,11-trimethyldodeca-2,6,10-trienylsulfanyl)benzoic acid | Salirasib, >=98% (HPLC) | AS-73028 | SMR004701762 | EU-0100517 | Farnesyl Thiosalicylic Acid | Farnesylthiosalicylic acid | Lopac-F-8175 | MLS006010835 | trans,t | ||
| CAS number | 162520-00-5 | molecular formula | C22H30O2S |
| molecular weight | 358.54 g/mol | Exact mass | 10mM in DMSO |
| PSA | 62.600 Ų | logp | 7.2 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P264: 处理后要彻底洗手。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。 P332+P317:
Production methods and uses
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downstream information
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MSDS
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