CAS number：587871-26-9 molecular formula：C21H17NO3S2
KU-55933是ATM抑制剂，IC50和Ki分别为13和2.2 nM，对DNA-PK，PI3K/PI4K，ATR和mTOR的活性较低。A cell-permeable, potent, selective and ATP-competitive ATM inhibitor KU-55933 (ATM Kinase Inhibitor) is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. A cell-permeable, potent, selective and ATP-competitive ATM inhibitor
| Chinese alias | - | ||
| English alias | KU-55933, >=98% (HPLC) | 2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | ATM Kinase Inhibitor | HMS3265N15 | HMS3413P10 | 2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one | HMS3244P07 | SCHEMBL1984941 | NCGC00263190-13 | BCP01834 | EC-000.1920 | HMS3244O0 | ||
| CAS number | 587871-26-9 | molecular formula | C21H17NO3S2 |
| molecular weight | 395.49 g/mol | Exact mass | - |
| PSA | 89.400 Ų | logp | 3.900 |
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