CAS number：115344-47-3 molecular formula：C14H16N6O
Siguazodan (SKF 94836) 是一种有效的，选择性的，口服活性的磷酸二酯酶 III (PDE-III) 抑制剂，IC50 为 117 nM。Siguazodan 可增加完整血小板中 cAMP 的积累，EC50 为 18.88 μM。Siguazodan 还抑制苯肾上腺素诱导的 5-HT 释放，IC50 值为 4.2 μM。 Siguazodan (SKF 94836) is a potent, selective and orally active phosphodiesterase III (PDE-III) inhibitor with an IC50 of 117 nM. Siguazodan increases cAMP accumulation in intact platelets with an EC50 of 18.88 μM. Siguazodan also inhibits phenylephrine-induced 5-HT release with an IC50 value of 4.2 μM.
| Chinese alias | N-氰基-N'-甲基-N''-[4-(1,4,5,6-四氢-4-甲基-6-氧代-3-哒嗪基)苯基]胍 | ||
| English alias | SR-01000075284-1 | AKOS024456417 | Dicarbethoxymethane | SkF94836 | SKF-94836 | Diaethylacetal | Guanidine, N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]- | GLXC-26081 | HMS2090J18 | NCGC00025032-04 | sec-Butyl ethanoat | ||
| CAS number | 115344-47-3 | molecular formula | C14H16N6O |
| molecular weight | 284.32 g/mol | Exact mass | - |
| PSA | 102.000 Ų | logp | 1.3 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
