5'-Fluoroindirubinoxime (compound 13) 是Indirubin (HY-N0117) 的衍生物,是FLT3 的抑制剂,其IC50 值为15 nM。
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5'-Fluoroindirubinoxime
Dangerous GoodsCAS number:861214-33-7 molecular formula:C16H10FN3O2
overview
compound introduction
Specs
| Chinese alias | 5'-氟-1H,1'H-[2,3']双二亚甲基-3,2'二酮3-肟 | ||
| English alias | 5'-Fluoro-1H | 1'H-[2,3']biindolylidene-3,2'dione 3-oxime | 5'-FIO | 5'-fluoro-3-(hydroxyamino)-1H,2'H-[2,3'-biindol]-2'-one | compound 13 | ||
| CAS number | 861214-33-7 | molecular formula | C16H10FN3O2 |
| molecular weight | 295.27 g/mol | Exact mass | - |
| PSA | 81.200 Ų | logp | 3.3 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
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MSDS
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