N-Ethylmaleimide-d 5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor.N-ethylmaleimide specific inhibits phosphate transport in mitochondria.N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor. In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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N-Ethylmaleimide-d5
Dangerous GoodsCAS number:360768-37-2 molecular formula:C6H7NO2
overview
compound introduction
Specs
| Chinese alias | N-乙基马来酰亚胺-d5 | ||
| English alias | N-Ethylmaleimide-d5 | HY-D0843S | MS-22774 | 1-[(1,1,2,2,2-?H?)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione | F90873 | N-Ethyl-d5-maleimide | 1-(1,1,2,2,2-pentadeuterioethyl)pyrrole-2,5-dione | N-Ethyl-d5-maleimide, 99 atom % D, 98% (CP) | SCHEMBL21751881 | ||
| CAS number | 360768-37-2 | molecular formula | C6H7NO2 |
| molecular weight | 130.16 g/mol | Exact mass | ≥99% |
| PSA | 37.400 Ų | logp | 0.9 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS06 , GHS08 , GHS05
Signal word:
Danger
Hazard Statement:
H314: 造成严重的皮肤灼伤和眼睛损伤 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 H312: 皮肤接触有害 H300: 吞咽致命
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P301+P310: 如误吞咽:立即呼叫急救中心/医生。 P310: 立即致电解毒中心或医生。 P264: 处理后要彻底洗手。
UN Number:
2928
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
360768-37-2 | N-Ethyl-d5-maleimide.pdf





