compound introduction
NS-638是具有阻断Ca2+-离子通道性质的非肽类小分子。细胞内阻断由K+激活的Ca2+浓度升高的IC50值为3.4 μM。 NS-638 is a small nonpeptide molecule with Ca2+-channel blocking properties. K+-stimulated intracellular Ca2+-elevation is blocked with an IC50 value of 3.4 μM.
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NS-638
Dangerous GoodsCAS number：150493-34-8 molecular formula：C15H11ClF3N3
overview
Specs
| Chinese alias | - | ||
| English alias | AKOS032947353 | 2-Amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole | 1H-Benzimidazol-2-amine, 1-((4-chlorophenyl)methyl)-5-(trifluoromethyl)- | BCP20747 | NS 638 | HY-101428 | 1H-Benzimidazol-2-amine, 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)- | ||
| CAS number | 150493-34-8 | molecular formula | C15H11ClF3N3 |
| molecular weight | 325.72 g/mol | Exact mass | ≥96% |
| PSA | 43.800 Ų | logp | 4.2 |
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physicochemical properties
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Safety information
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。
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MSDS
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