PF-03814735是有效,有口服性,ATP 竞争性的,可逆的极光激酶A和B (aurora A/B) 的抑制剂,IC50值分别为0.8和5 nM。 Product Describtion: PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively.
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PF-03814735
Dangerous GoodsCAS number:942487-16-3 molecular formula:C23H25F3N6O2
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Specs
| Chinese alias | - | ||
| English alias | UNII-6V5T4O5758 | NSC801015 | NSC-801015 | DTXSID601025621 | C23H25F3N6O2 | Q27265567 | PF03814735 | PF-03814735 | s2725 | PF 03814735 [WHO-DD] | Z3041529866 | N-(2-((1S,4R)-6-((4-(Cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1,2,3,4-tetrahyd | ||
| CAS number | 942487-16-3 | molecular formula | C23H25F3N6O2 |
| molecular weight | 474.48 g/mol | Exact mass | ≥98% |
| PSA | 99.300 Ų | logp | 3 |
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WGK Germany:
3
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