compound introduction
PF-431396是双PYK2/FAK抑制剂，IC50分别为11nM和2 nM。 PF-431396 is a dual PYK2/FAK inhibitor with IC50 of 11 nM and 2 nM, respectively. A dual inhibitor of FAK (focal adhesion kinase) and PYK2.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
PF-431396
Dangerous GoodsCAS number：717906-29-1 molecular formula：C22H21F3N6O3S
overview
Specs
| Chinese alias | - | ||
| English alias | CCG-221509 | s7644 | DTXSID50469204 | BDBM50246060 | HY-10460 | N-methyl-N-{2-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]phenyl}methanesulfonamide | HMS3244D08 | EX-A787 | NCGC00370948-06 | PF431396 | PF-4 | ||
| CAS number | 717906-29-1 | molecular formula | C22H21F3N6O3S |
| molecular weight | 506.5 g/mol | Exact mass | 10mM in DMSO |
| PSA | 125.000 Ų | logp | 2.800 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS06 , GHS07
Signal word：
Danger
Hazard Statement：
H319: 引起严重眼睛刺激 H301: 吞咽会中毒
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
