compound introduction
ZM39923盐酸盐是一种JAK1/3抑制剂, pIC50 of 4.4/7.1, 对JAK2几乎没有抑制活性。 ZM 39923 HCl is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
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ZM 39923 HCl
Dangerous GoodsCAS number：1021868-92-7 molecular formula：C23H25NO.HCl
overview
Specs
| Chinese alias | 3-(异丙基(苄基)氨基)-1-(2-萘基)-1-丙酮盐酸盐 | ||
| English alias | DTXSID301017077 | 3-BENZYLISOPROPYLAMINO-1-NAPHTHALEN-2-YL-PROPAN-1-ONE HYDROCHLORIDE | ZM39923 HCl;ZM-39923 HCl | 3-(N-Benzyl-N-isopropyl)amino-1-(naphthalen-2-yl)propan-1-one, hydrochloride | AC-30261 | ZM 39923 hydrochloride; Jak3 inhibitor IV | ZM3992 | ||
| CAS number | 1021868-92-7 | molecular formula | C23H25NO.HCl |
| molecular weight | 367.91 g/mol | Exact mass | - |
| PSA | 20.300 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
Signal word：
警告
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
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MSDS
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