BLU9931是一种有效的,选择性的,且不可逆的 FGFR4 抑制剂,IC50 为 3 nM,选择性比作用于 FGFR1/2/3分别高 297,184,和 50倍。
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BLU-9931
Dangerous GoodsCAS number:1538604-68-0 molecular formula:C26H22Cl2N4O3
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | B0084-470871 | BLU 9931 [WHO-DD] | N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)-3-methylphenyl)acrylamide | A900737 | AS-55995 | BLU 9931 | HMS2052A05 | HY-12823 | FQK825B5DX | 2-Propenamide, N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl | ||
| CAS number | 1538604-68-0 | molecular formula | C26H22Cl2N4O3 |
| molecular weight | 509.384 g/mol | Exact mass | - |
| PSA | 85.400 Ų | logp | 6.400 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
Production methods and uses
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downstream information
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MSDS
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