compound introduction
乳糖基神经酰胺中性鞘糖脂（GSL），是GSL神经节，球蛋白，球蛋白，乳酸，新乳胶和粘液系列的常见前体。通过ERK 1（p44 MAP激酶）的特异性激活，促进主动脉平滑肌细胞的时间依赖性和浓度依赖性增殖。还刺激人主动脉平滑肌细胞中的Ras-GTP加载，MEK和Raf激酶，p44 MAP激酶和c-fos表达。 Lactosyl Ceramide neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of ERK 1 (p44 MAP kinase). Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.
