compound introduction
Linderalactone 是从 Radix linderae 中分离出来的一种重要的倍半萜烯内酯。Linderalactone 通过调节凋亡相关蛋白的表达和抑制 JAK/STAT 信号通路来抑制癌细胞生长。Linderalactone 还以 IC50 值为 15 µM 来抑制肺癌 A-549 细胞的增殖。
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Isolinderalactone
CAS number：728-61-0 molecular formula：C15H16O3
overview
Specs
| Chinese alias | - | ||
| English alias | (R,7Z,10E)-3,11-dimethyl-4,8,9,12-tetrahydro-6H-4,7-(metheno)furo[3,2-c][1]oxacycloundecin-6-one | AC-34847 | Linderalactone | AKOS015897170 | (1R,8E)-3,8-dimethyl-5,14-dioxatricyclo[10.2.1.0?,?]pentadeca-2(6),3,8,12(15)-tetraen-13-one | HY-N0781 | LWCKQM | ||
| CAS number | 728-61-0 | molecular formula | C15H16O3 |
| molecular weight | 244.29 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 39.400 Ų | logp | 2.700 |
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728-61-0 | Linderalactone.pdf
