溶血磷脂酰胆碱是氧化的低密度脂蛋白的主要成分，与多种炎症反应有关，包括动脉粥样硬化。它用于使脊髓神经元脱髓鞘并研究髓鞘再生的过程。它激活蛋白激酶C，p38 MAP激酶，p42 MAP激酶和jun激酶（JNK）途径，并刺激c-jun的转录。溶血磷脂酰胆碱在心脏缺血期间积累，并可能通过解偶联间隙连接通讯而诱发心律不齐，并通过增强心肌细胞中的Na +负荷而增加缺血性损害。它还激活TREK1，TREK2和TRAAK K +通道。 产品应用： 来自蛋黄的L-α-溶血磷脂酰胆碱已被用于： 作为表面活性剂 作为培养基补充剂以及用于皮炎的金黄色葡萄球菌（Staphylococcus aureus）抑制试验 作为神经脱髓鞘剂 作为精子细胞核制备缓冲液的组分 Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
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L-α-Lysophosphatidylcholine (from egg yolk)
Dangerous GoodsCAS number：9008-30-4 molecular formula：
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | GTPL2508 | Lysophosphatidylcholine, soybean | Lysophosphatidylcholine | [(2R)-3-acetyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | [(2R)-3-acetyloxy-2-hydroxypropyl] 2-trimethylazaniumylethyl phosphate | UNII-CQD833204Z | Q27083304 | CQD83 | ||
| CAS number | 9008-30-4 | molecular formula | |
| molecular weight | 299.260 g/mol | Exact mass | - |
| PSA | 105.000 Ų | logp | -1.800 |
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physicochemical properties
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Safety information
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
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No production method and use information yet
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MSDS
Found 1 shareMSDS
9008-30-4 | L-α-Lysophosphatidylcholine, from egg yolk.pdf
