CAS number：328998-25-0 molecular formula：C28H18N2O6
4E1RCat是一种蛋白质翻译抑制剂，已被证明可以阻止eIF4E：eIF4G和eIF4E：4E-BP1相互作用。该化合物阻止eIF4F复合物的组装并抑制帽依赖性翻译。 4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction. This compound blocks assembly of the eIF4F complex and inhibits cap-dependent translation. Application： 4E1RCat was used to inhibit new protein synthesis in transformed primary chicken embryo fibroblasts.
| Chinese alias | - | ||
| English alias | 4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid | ||
| CAS number | 328998-25-0 | molecular formula | C28H18N2O6 |
| molecular weight | 478.45 g/mol | Exact mass | 10mM in DMSO |
| PSA | 117.000 Ų | logp | 5.300 |
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