PF-04457845是FAAH选择性抑制剂,IC50为7.2 nM,具有镇痛和抗炎活性。 PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.
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PF-04457845
Dangerous GoodsCAS number:1020315-31-4 molecular formula:C23H20F3N5O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | N-pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzylidene)piperidine-1-carboxamide | s2421 | HY-14376 | N-Pyridazin-3-yl-4-((3-(5-(trifluoromethyl)pyridin-2-yl)oxyphenyl)methylidene)piperidine-1-carboxamide | PF04457845 | PF-04457845 | AC-36 | ||
| CAS number | 1020315-31-4 | molecular formula | C23H20F3N5O2 |
| molecular weight | 455.43 g/mol | Exact mass | - |
| PSA | 80.200 Ų | logp | 3.3 |
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WGK Germany:
3
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