CAS number：315704-66-6 molecular formula：C17H13Br2N5OS
应用： PTC-209已被用作B淋巴瘤Mo-MLV插入区1同源物（BMI1）抑制剂，用于研究其对以下方面的影响： 犬骨肉瘤（OSA）细胞系的细胞活力 卵巢癌（OvCa）细胞中脂质化的微管相关蛋白1轻链3（LC3B-II）和死骨片1（SQSTM1）蛋白的水平 小鼠胚胎成纤维细胞（MEF）的心脏重编程效率。 product description： PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).
| Chinese alias | N-(2,6-二溴-4-甲氧基苯基)-4-(2-甲基咪唑并[1,2-a]嘧啶-3-基)-2-噻唑胺 | ||
| English alias | FT-0700288 | Oprea1_578634 | EN300-175183 | PTC209 | PTC-209 | AS-16950 | s7372 | AC-32640 | BCP09028 | HY-15888 | N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine | C17H13Br2N5OS | HMS3653M18 | PTC 209 | Oprea1_5891 | ||
| CAS number | 315704-66-6 | molecular formula | C17H13Br2N5OS |
| molecular weight | 495.19 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 92.600 Ų | logp | 5.500 |
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