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PF-8380

Dangerous Goods

CAS number:1144035-53-9    molecular formula:C22H21Cl2N3O5

overview

compound introduction

PF-8380是高活性的autotaxin特异性抑制剂,IC50为2.8 nM。 PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM. A substrate competitive and tight-binding inhibitor of autotaxin.

Specs

Chinese alias-
English aliasHMS3740G07 | 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester | CCG-269523 | 3,5-Dichlorobenzyl-[4-[3-oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]]piperazine-1-carboxylate | 1-Piperazinecarboxyli
CAS number1144035-53-9molecular formulaC22H21Cl2N3O5
molecular weight478.33 g/molExact mass-
PSA88.200 Ųlogp3.200

numbering system

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physicochemical properties

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Safety information

WGK Germany:
3

Production methods and uses

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upstream information

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downstream information

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MSDS

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