PF-8380是高活性的autotaxin特异性抑制剂,IC50为2.8 nM。 PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM. A substrate competitive and tight-binding inhibitor of autotaxin.
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PF-8380
Dangerous GoodsCAS number:1144035-53-9 molecular formula:C22H21Cl2N3O5
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | HMS3740G07 | 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester | CCG-269523 | 3,5-Dichlorobenzyl-[4-[3-oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]]piperazine-1-carboxylate | 1-Piperazinecarboxyli | ||
| CAS number | 1144035-53-9 | molecular formula | C22H21Cl2N3O5 |
| molecular weight | 478.33 g/mol | Exact mass | - |
| PSA | 88.200 Ų | logp | 3.200 |
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WGK Germany:
3
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