胆酸盐是由肝脏中的胆固醇产生的初级胆汁酸。它是在固醇12α-羟化酶（CYP8B1）存在的情况下由胆固醇合成的一种阴离子洗涤剂。水合胆酸钠是一种生物表面活性剂，可作为水溶液中的还原剂。非变性去垢剂用于抽提膜蛋白。 已有研究关于采用水合胆酸钠研究磷脂配方和表面活性剂对弹性脂质体亲水性药物真皮给药的影响。 它也被用于一项研究用于经皮给药的弹性变形囊泡，转移体研究。 用途： 胆酸盐是肝脏在胆固醇分解过程中产生的一种胆酸。胆酸盐向下调节胆固醇-7α-羟化酶（胆汁酸合成中的限速步骤）。 胆酸盐是一种阴离子洗涤剂，可单独使用或与尿素一起使用，用于提取和重建膜蛋白和蛋白复合物。 胆酸钠水合物已被用于： 作为胆汁酸用于诱导胆汁酸响应（BEAR）转录系统, 作为弯曲杆菌确定成分肉汤（CDB）的成分用于测试其对空肠弯曲杆菌i{52应激反应的影响 测试其对胆汁酸传感器的敏感性； Cholate is a primary bile acid produced from cholesterol in the liver. It is an anionic detergent synthesized from cholesterol in the presence of sterol 12α-hydroxylase (CYP8B1). Application： Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes. Sodium cholate hydrate has been used: as a bile acid to induce bile acid-responsive (BEAR) transcription system, as a component of Campylobacter defined broth (CDB) to test its effect on stress response in Campylobacter jejuni{52 to test its sensitivity towards the bile acid sensor;
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Sodium cholate hydrate
Dangerous GoodsCAS number：206986-87-0 molecular formula：C24H39NaO5 · xH2O
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| Chinese alias | 胆酸钠 水合物 | 3α,7α,12α-三羟基-5β-胆甾烷-24-羧酸 钠盐 | 胆酸钠盐 | ||
| English alias | 2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate hydrate | ||
| CAS number | 206986-87-0 | molecular formula | C24H39NaO5 · xH2O |
| molecular weight | 430.55 (anhydrous ba | Exact mass | 用于细胞培养 |
| PSA | 102.000 Ų | logp | - |
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Safety information
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
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206986-87-0 | Sodium cholate hydrate | Sodium cholate hydrate
