Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.Oxidizes uric acid Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment. Oxidizes uric acid
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尿酸酶 来源于产朊假丝酵母
Dangerous GoodsCAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 尿酸酶 | ||
| English alias | FT-0772402 | Uricase from Bacillus fastidiosus, lyophilized, ~9 U/mg | Uricase from Candida sp., recombinant, expressed in E. coli, lyophilized powder, >=2 units/mg solid | VPXDHZMLJOJKOX-UHFFFAOYSA-N | Uricase from Arthrobacter globiformis, lyophilized p | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | - |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS08
Signal word：
Danger
Hazard Statement：
H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P501: 将内容物/容器处理到。。。 P284: 如果通风不良，请佩戴呼吸防护装置。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P342+P316: 如果出现呼吸道症状：立即寻求急救。
WGK Germany：
3
Personal protective equipment：
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS：
YU7100000
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
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