生物活性: aPKC-IN-2是一种小分子抑制剂,具有抑制aPKC活性。 在细胞培养和体内实验中有效阻断血管内皮通透性; 在干预NFκB驱动的基因转录方面显示出生物活性; 对VEGF和TNF诱导的血管内皮通透性有显著抑制作用 aPKC-IN-2 is a small molecule inhibitor that inhibits aPKC activity. Effectively blocking vascular endothelial permeability in cell culture and in vivo experiments; Shows biological activity in intervening in NF κ B driven gene transcription Significant inhibitory effect on vascular endothelial permeability induced by VEGF and TNF
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Ethyl 2-amino-4-p-tolylthiophene-3-carboxylate
Dangerous GoodsCAS number:15854-08-7 molecular formula:C14H15NO2S
overview
compound introduction
Specs
| Chinese alias | 2-氨基-4-(对甲苯基)噻吩-3-羧酸乙酯 | ||
| English alias | Oprea1_417516 | 2-Amino-3-(ethoxycarbonyl)-4-(4-methylphenyl)thiophene | ETHYL2-AMINO-4-(4-METHYLPHENYL)-3-THIOPHENECARBOXYLATE | SCHEMBL690278 | 2-amino-4-(4-methylphenyl)-thiophene-3-carboxylic acid ethyl ester | 2-amino-4-(4-methylphenyl)thiophene-3-ca | ||
| CAS number | 15854-08-7 | molecular formula | C14H15NO2S |
| molecular weight | 261.34 g/mol | Exact mass | - |
| PSA | 80.600 Ų | logp | 4 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水
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MSDS
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