Cyclo(his-pro) (Cyclo(histidyl-proline)) 是一种 结构上与促甲状腺激素释放激素相关的环状二肽。Cyclo(his-pro) 可以抑制 NF-κB 核积累。Cyclo(his-pro) 可以穿越脑血屏障并影响多种炎症和应激反应。 Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses. Application: Cyclo(L-His-L-Pro) is a versatile molecule and it finds application in biochemical and metabolomics research.
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Cyclo(-His-Pro)
Dangerous GoodsCAS number:53109-32-3 molecular formula:C11H14N4O2
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Specs
| Chinese alias | 环(-组氨酸-脯氨酸) | ||
| English alias | Cyclo(his-pro) | Histidylproline diketopiperazine | Cyclo(L-histidyl-L-proline) | Histidylproline dioxopiperazine | Cyclo(histidyl-proline) | Cyclo(prolylhistidine) | ||
| CAS number | 53109-32-3 | molecular formula | C11H14N4O2 |
| molecular weight | 234.26 g/mol | Exact mass | ≥98% |
| PSA | 78.100 Ų | logp | -0.4 |
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WGK Germany:
3
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