CAS number：190648-49-8 molecular formula：C22H36N4O5
Ro 32-3555是一种有效的胶原酶选择性MMP抑制剂（对于MMP-1，MMP-13，MMP-8，MMP-9，MMP，K | i |值为3.0、3.4、4.4、59、154和527 nM -2和MMP-3）。已显示出在体外和体内抑制软骨分解并显示出抗关节炎活性。 Ro 32-3555 is a potent, collagenase-selective MMP inhibitor (K|i|values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3, respectively). Shown to inhibit cartilage breakdown|in vitro|and|in vivo|and displays antiarthritic activity.
| Chinese alias | - | ||
| English alias | Trocade | Trocade (TN) | N-(tert-Butoxycarbonyl)-3-[4-(2,6-dichlorobenzyloxy)phenyl]alanine | Ro-323555000 | (alphaR,betaR)-beta-(Cyclopentylmethyl)-gamma-oxo-alpha-((3,4,4-piperidinebutyrohydroxamic acid | (alphaR,betaR)-beta-(Cyclopentylmethyl)-gamma-ox | ||
| CAS number | 190648-49-8 | molecular formula | C22H36N4O5 |
| molecular weight | 436.55 g/mol | Exact mass | - |
| PSA | 110.000 Ų | logp | 1.6 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
