卤培米特是多巴胺抑制剂和PC-PLD2（磷脂酶D2）抑制剂。使用体外生化测定法，可以将卤培米特用作筛选剂来鉴定人PLD2的抑制剂。在苯并二氮杂pine结合位点也具有抑制作用。卤培米特是PC-PLD1（PLD1）的抑制剂。 Halopemide is a dopamine inhibitor and a PC-PLD2 (phospholipase D2) inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay. It is also inhibitory at benzodiazepine binding sites. Halopemide is an inhibitor of PC-PLD1 (PLD1). Application： Halopemide, a non-specific phospholipase D (PLD) antagonist, may be used with selective PLD antagonists (CAY10593, a PLD1 antagonist; CAY10594 or ML298, selective PLD2 antagonist) to help define the role and physiological effects regulated by phospholipase D enzymes. Halopemide may be used as the basis of the design and development of more selective PLD antagonists.
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Halopemide
Dangerous GoodsCAS number：59831-65-1 molecular formula：C21H22ClFN4O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | SR-01000946369 | Halopemidum | N-(2-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-fluorobenzamide | VU0155067-2 | MLS006012046 | Halopemida [INN-Spanish] | HMS3648G20 | MLS003171133 | N-[2-[4-(5-Chloro-2-oxo-1-benzimidazo | ||
| CAS number | 59831-65-1 | molecular formula | C21H22ClFN4O2 |
| molecular weight | 416.88 g/mol | Exact mass | ≥97% |
| PSA | 64.700 Ų | logp | 3.7 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
WGK Germany：
3
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MSDS
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