CAS number：24150-24-1 molecular formula：C22H30O4
四甲基去甲二氢愈创木酸是NDGA的合成衍生物，是一种非选择性的LO（lipoxygenase）抑制剂。四甲基去甲二氢愈创木酸抑制在HIV长末端重复序列启动子和α-ICP4启动子（HSV复制所必需的基因）的Sp1转录因子结合。 Tetramethyl Nordihydroguaiaretic Acid is a synthetic derivative of NDGA and a non-selective LO (lipoxygenase) inhibitor. Tetramethyl Nordihydroguaiaretic Acid inhibits Sp1 transcription factor binding at the HIV long terminal repeat promoter and at the α-ICP4 promoter (a gene essential for HSV replication).
| Chinese alias | - | ||
| English alias | D09014 | UNII-53YET703F2 | Tmndga | DB12226 | 1,4-BIS(3,4-DIMETHOXYPHENYL)-2,3-DIMETHYL-, MESO- | 4-[(2S,3R)-4-(3,4-dimethoxyphenyl)-2,3-dimethyl-butyl]-1,2-dimethoxy-benzene | 4-[(2S,3R)-4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxybenzene | E | ||
| CAS number | 24150-24-1 | molecular formula | C22H30O4 |
| molecular weight | 358.47 g/mol | Exact mass | - |
| PSA | 36.900 Ų | logp | 5.6 |
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