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GLX351322

Dangerous Goods

CAS number：835598-94-2    molecular formula：C21H25N3O5S

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overview

compound introduction

GLX351322 是一种 NADPH 氧化酶 4 (Nox4) 抑制剂，在 NOX4 过表达的细胞中，抑制过氧化氢的产生，IC50 值为 5 μM。 Information GLX351322 GLX351322 is a NADPH oxidase 4 (NOX4) inhibitor. GLX351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells with IC50 of 5 μM. Targets NOX4 (Cell-free assay) 5 μM

Specs

Chinese alias-
English alias4H-​Cyclopenta[b]​thiophene-​3-​carboxylic acid,2-​[[2-​[4-​(2-​furanylcarbonyl)​-​1-​piperazinyl]​acetyl]​amino]​-​5,​6-​dihydro-​,ethyl ester
CAS number835598-94-2molecular formulaC21H25N3O5S
molecular weight431.51 g/molExact mass10mM in DMSO
PSA120.000 Ųlogp2.15

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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