compound introduction
Information Mito-TEMPO Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced RIP3 kinase expression. Targets RIP3 kinase In vitro Mito-TEMPO improves blastocyst development by superoxide reduction in porcine embryos in vitro. In vivo Mito-Tempo (MT) treatment inhibits APAP-induced RIP3 kinase expression, and RIP3-deficient mice shows caspase activation and apoptotic morphology in hepatocytes analogous to MT treatment. Cell Research(from reference) Cell lines：Porcine embryos Concentrations：0.1\u2009μM
