CAS number：1189767-28-9 molecular formula：C16H17N5O2
Information BI-409306 BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with mean IC50 of 65 nM and 168 nM, respectively. Treatment with BI 409306 increases brain cGMP levels, promotes long-term potentiation, and improves episodic and working memory performance in rodents. Targets human PDE9A (Cell-free assay); rat PDE9A (Cell-free assay) 65 nM; 168 nM
| Chinese alias | - | ||
| English alias | O9OC34WOAY | 6-(Pyridin-2-ylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | UNII-O9OC34WOAY | AKOS040759436 | MS-24536 | Osoresnontrine [INN] | SCHEMBL7885817 | AC-36258 | BI-409306 | EX-A2733 | SUB 166499 | HY-112831 | ||
| CAS number | 1189767-28-9 | molecular formula | C16H17N5O2 |
| molecular weight | 311.34 g/mol | Exact mass | ≥99% |
| PSA | 81.400 Ų | logp | 0.421 |
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