2′,7′-Dichlorofluorescin Diacetate is a cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) and nitric oxide (NO) and for the determination of the degree of overall oxidative stress. 它是一种细胞可渗透的非荧光探针。2′,7′-二氯荧光素二乙酸酯是在细胞内脱酯化的并可经氧化转化为具有强荧光的2′,7′-二氯荧光素。 应用包括响应氧化代谢的活性氧的灵敏快速定量；用于吞噬细胞中的氧化产物的微孔板检测，以及定量多孔髓样分化测定。 2′,7′-Dichlorofluorescin Diacetate is a cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) and nitric oxide (NO) and for the determination of the degree of overall oxidative stress. For maximum solubility in aqueous buffers, DCFH-DA can be directly disolved in 0.1 M Na2CO3 (5 mg/ml) and then immediately diluted with PBS (pH 7.2) to achieve the desired concentration or pH. Upon neutralization of the solution the concentration may not be greater than 1 mg/ml. We do not recommend storing the aqueous solution for more than one day.
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2',7'-Dichlorodihydrofluorescein diacetate(DCFH-DA)
Dangerous GoodsCAS number：4091-99-0 molecular formula：C24H16Cl2O7
overview
compound introduction
Specs
| Chinese alias | 2′,7′-二氯二氢荧光素二乙酸酯 | 2',7'-二氯荧光素二乙酸酯 | 2-(3,6-二乙酰氧基-2,7-二氯氧杂蒽-9-基)苯甲酸 | ||
| English alias | A03-0014 | 2',7'-Dichlorohydrofluorescein diacetate | BW12C79 | SCHEMBL12361545 | 2-(3,6-diacetoxy-2,7-dichloro-9h-xanthen-9-yl)benzoic acid | 2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic Acid | SY075534 | 2,7-Dichlorodihydrofluoresceindiace | ||
| CAS number | 4091-99-0 | molecular formula | C24H16Cl2O7 |
| molecular weight | 487.286 g/mol | Exact mass | ≥97% |
| PSA | 99.100 Ų | logp | 5.200 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
4091-99-0 | 2′,7′-Dichlorofluorescin Diacetate.pdf
