compound introduction
Application Raphin1 is an orally bioavailable, selective inhibitor of R15B (PPP1R15B, a regulatory subunit of protein phosphatase 1). Raphin1 binds strongly to the R15B-PP1c holophosphatase with Kd of 33 nM.
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Raphin 1
Dangerous GoodsCAS number：2022961-17-5 molecular formula：C8H8Cl2N4
overview
Specs
| Chinese alias | (2E)-2-[((2,3-二氯苯基)亚甲基]肼羧酰亚胺 | ||
| English alias | 2-(2,3-Dichlorobenzylidene)hydrazine-1-carboximidamide | BDBM50545524 | 3-[(2,3-DICHLOROPHENYL)METHYLENE]CARBAZAMIDINE | EN300-25957086 | N-[(E)-[(2,3-dichlorophenyl)methylidene]amino]guanidine | Pyridine, 3-(2-pyrrolidinyl)-,(S)- | (E)-2-(2,3-Dichloroben | ||
| CAS number | 2022961-17-5 | molecular formula | C8H8Cl2N4 |
| molecular weight | 231.08 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 76.800 Ų | logp | 1.700 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水
Production methods and uses
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MSDS
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