compound introduction
Safinamide (EMD 1195686; FCE 26743)是可逆的MAO-B抑制剂，IC50为98 nM，比对MAO-A的抑制性高5918倍。 Safinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A.
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Safinamide
Dangerous GoodsCAS number：133865-89-1 molecular formula：C17H19FN2O2
overview
Specs
| Chinese alias | 沙芬酰胺 | 沙芬酰胺 | ||
| English alias | DTXCID701436700 | CHEBI:134718 | D10158 | (S)-2[4-(3-fluorobenzyloxy)benzylamino] propanamide | BDBM50078694 | Q2211523 | SAFINAMIDE [INN] | 2(S)-[4-(3-Fluorobenzyloxy) benzylamino] propionamide | NEMGRZFTLSKBAP-LBPRGKRZSA-N | (S)-2-[4-(3-fluorobenzyloxy) | ||
| CAS number | 133865-89-1 | molecular formula | C17H19FN2O2 |
| molecular weight | 302.34 g/mol | Exact mass | - |
| PSA | 64.400 Ų | logp | 2.2 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06 , GHS09 , GHS05
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒 H318: 造成严重的眼睛损伤 H400: 对水生生物有剧毒
Statement of Preventive Measures：
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟
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downstream information
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MSDS
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