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Physostigmine salicylate

Dangerous Goods

CAS number:57-64-7    molecular formula:C15H21N3O2・C7H6O3

overview

compound introduction

毒扁豆碱水杨酸酯是毒扁豆碱的衍生物。毒扁豆碱是一种原始生物,起源于卡拉巴尔豆(| Physostigma venenosum |),并被认为是有效且可逆的胆碱酯酶抑制剂。毒扁豆碱还被报道与乙酰胆碱酯酶(AChE)形成缓慢降解的氨基甲酸酯化酶复合物。在研究乙酰胆碱酯酶抑制剂潜在抗蠕虫药靶标的研究中,该化合物已用作阳性对照。另外,据报道,这种拟副交感神经化合物可穿越血脑屏障。 Physostigmine salicylate is a derivative of Physostigmine . Physostigmine is an alkaloid originally derived from the Calabar bean (|Physostigma venenosum|) and noted to act as a potent and reversible inhibitor of cholinesterase. Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). This compound has been used as a positive control in a study investigating acetylcholinesterase inhibitors for potential antihelminthic drug targets. Additionally, this parasympathomimetic compound is reported to cross the blood-brain barrier.

Specs

Chinese alias毒扁豆碱 水杨酸盐 | 吡咯他尼杂质A | 水杨酸依色林
English aliasEserine salicylate
CAS number57-64-7molecular formulaC15H21N3O2・C7H6O3
molecular weight413.47 g/molExact mass-
PSA102.000 Ųlogp-

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS06
Signal word:
危险
Hazard Statement:
H300: 吞咽致命 H330: 吸入致命
Statement of Preventive Measures:
P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良,请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P330: 漱口 P320: 迫切
UN Number:
2811
Packing Group:

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MSDS

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