应用 异丁基溴化锌是有机锌化合物,可用作试剂,在钯催化的Negishi交叉偶联反应中,通过与芳基或杂芳基卤化物 反应构建碳-碳键。 也用于在镍催化剂存在的情况下,通过烯丙基羰基偶合反应,与叔丁基异氰酸酯反应制备区域选择性不饱和酮。 Description Isobutylzinc bromide is an organozinc compound, which can be used as a reagent in the palladium-catalyzed Negishi cross-coupling reaction to construct a carbon-carbon bond by reacting with aryl or heteroaryl halides . It is also used to prepare regioselective unsaturated ketones by reacting withtert-butyl isocyanide via an allylic carbonylative coupling reaction in the presence of a nickel catalyst.
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Isobutylzinc bromide solution
Dangerous GoodsCAS number:126403-67-6 molecular formula:(CH3)2CHCH2ZnBr
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 126403-67-6 | molecular formula | (CH3)2CHCH2ZnBr |
| molecular weight | 202.41 g/mol | Exact mass | 0.5M in THF |
| PSA | 0.000 Ų | logp | - |
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physicochemical properties
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Safety information
pictogram:
GHS08 , GHS07 , GHS02
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H351: 怀疑引起遗传缺陷 H302: 吞食有害 H225: 高度易燃的液体和蒸气 H261: 与水接触释放出易燃气体
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P231+P232: 在惰性气体中操作。防潮。 P370+P378: 火灾时:使用干砂、干粉或抗醇泡沫灭火。 P210: 远离热源,热表面,火花,明火和其他点火源。 - 禁止抽烟。 P403+P235: 存放在通风良好的地方。保持低温。 P402+P404: 存放于干燥处。存放于密闭的容器中。
WGK Germany:
3
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