compound introduction
Rilpivirine (R278474) 是一种有效和特异性的二芳基嘧啶 (DAPY) 非核苷逆转录酶抑制剂 (NNRTI)。Rilpivirine 对野生型 HIV (EC50=0.4 nM) 和突变体 (EC50=0.1-2.0 nM) 具有很高的抗病毒活性。Rilpivirine 对 HIV 耐药性的形成产生了高度的遗传障碍。
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Rilpivirine
Dangerous GoodsCAS number：500287-72-9 molecular formula：C22H18N6
overview
Specs
| Chinese alias | 利吡韦林 | ||
| English alias | 4-{[4-({4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile | AC-30619 | W-202888 | R278474;TMC278 | GTPL11387 | MFCD11046372 | YIBOMRUWOWDFLG-ONEGZZNKSA-N | EN300-21682062 | R278474 | R-278474 | Rilpivirine [INN] | RILPIVIR | ||
| CAS number | 500287-72-9 | molecular formula | C22H18N6 |
| molecular weight | 366.42 g/mol | Exact mass | - |
| PSA | 97.400 Ų | logp | 4.5 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS09 , GHS07
Signal word：
Warning
Hazard Statement：
H319: 引起严重眼睛刺激 H302: 吞食有害 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P337+P317:
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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