CAS number：451462-58-1 molecular formula：C16H21N3O2S
H-1152是特异的高活性Rho激酶抑制剂，可渗透入细胞膜，Ki为1.6 nM，对其它丝氨酸/苏氨酸激酶抑制性极低。A cell permeable, highly specific, and potent ATP-competitive inhibitor of ρ-kinase inhibitor。 H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases. A cell permeable, highly specific, and potent ATP-competitive inhibitor of ρ-kinase inhibitor。
| Chinese alias | - | ||
| English alias | DTXSID20735620 | Methyl (2S)-2-{[(benzyloxy)carbonyl]-amino}-3-hydroxypropanoate | dimethylfasudil | SCHEMBL124161 | NCGC00378616-03 | H-1152P | HY-15720 | 4-methyl-5-{[(2S)-2-methyl-1,4-diazepane-1-]sulfonyl}isoquinoline | 2gnh | H52 | 4-methyl-5-[(2S)-2 | ||
| CAS number | 451462-58-1 | molecular formula | C16H21N3O2S |
| molecular weight | 319.42 g/mol | Exact mass | ≥98% |
| PSA | 70.700 Ų | logp | 1.7 |
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