Vactosertib (TEW-7197, EW-7197)是一种高效的,选择性的TGF-β receptor ALK4/ALK5抑制剂,IC50分别为13 nM 和 11 nM。
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Vactosertib (TEW-7197)
Dangerous GoodsCAS number:1352608-82-2 molecular formula:C22H18FN7
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | AC-29028 | W-200739 | 1352608-82-2 | SB17272 | MFCD28348363 | N-[[4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1h-imidazol-2-yl]methyl]-2-fluoroaniline | UNII-6T4O391P5Y | 6T4O391P5Y | HY-19928 | s7530 | VACTOSERTIB [INN] | AKOS02725074 | ||
| CAS number | 1352608-82-2 | molecular formula | C22H18FN7 |
| molecular weight | 399.43 g/mol | Exact mass | - |
| PSA | 83.800 Ų | logp | 3.2 |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
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