Azaindole 1是有口服活性,ATP-竞争型的 ROCK 抑制剂,对ROCK-1 和 ROCK-2 的 IC50 值分别为0.6 和 1.1 nM。
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TC-S 7001
Dangerous GoodsCAS number:867017-68-3 molecular formula:C18H13ClF2N6O
overview
compound introduction
Specs
| Chinese alias | 6-氯-N4-[3,5-二氟-4-[(3-甲基-1H-吡咯并[2,3-b]吡啶-4-基)氧基]苯基] -2,4-嘧啶二胺 | 氮杂吲哚 1 | ||
| English alias | BAY-549 | BDBM412136 | Azaindole 1 | HY-10319 | AKOS015920124 | ROCK-IN-2TC-S 7001 | 6-Chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine | Azaindole-1 | C18H13ClF2N6O | CCG-142806 | MFCD15528941 | TC-S 70 | ||
| CAS number | 867017-68-3 | molecular formula | C18H13ClF2N6O |
| molecular weight | 402.79 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 102.000 Ų | logp | 4.200 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
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MSDS
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