compound introduction
PK11000 是一种烷化剂，可通过共价半胱氨酸修饰来稳定野生型和突变型 p53 的 DNA 结合结构域，而不影响 DNA 的结合。
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PK11000
Dangerous GoodsCAS number：38275-34-2 molecular formula：C6H5ClN2O4S
overview
Specs
| Chinese alias | 5-氯-2-(甲基磺酰基)嘧啶-4-羧酸 | ||
| English alias | HY-U00447 | SY059860 | BCP30143 | CCG-266846 | EX-A3577 | AKOS000267675 | 5-chloro-2-(methylsulfonyl)-4-Pyrimidinecarboxylic acid | 5-chloro-2-methylsulfonylpyrimidine-4-carboxylic acid | A873890 | 5-chloro-2-methanesulfonyl-pyrimidine-4-carboxylic acid | | ||
| CAS number | 38275-34-2 | molecular formula | C6H5ClN2O4S |
| molecular weight | 236.63 g/mol | Exact mass | 10mM in DMSO |
| PSA | 106.000 Ų | logp | 0.300 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水
Production methods and uses
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MSDS
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