All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

WP1066

Dangerous Goods

CAS number：857064-38-1    molecular formula：C17H14BrN3O

overview
Specs
numbering system
physicochemical properties
Safety information
Production methods and uses
Related
MSDS
related products

overview

compound introduction

WP1066是一种新型JAK2和STAT3抑制剂，在HEL细胞中IC50分别为2.30 μM和2.43 μM；对JAK2，STAT3，STAT5和ERK1/2具有抑制活性，而对JAK1和JAK3没有作A cell permeable inhibitor of Stat3 and JAK2 protein tyrosine kinase. WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. A cell permeable inhibitor of Stat3 and JAK2 protein tyrosine kinase.

Specs

Chinese alias-
English aliasAKOS016007983 | AC-28413 | GTPL7972 | MFCD00445901 | 63V8AIE65T | BDBM50557738 | MLS006010178 | SCHEMBL1315831 | STK888392 | Q27089227 | UNII-63V8AIE65T | (S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide | 1-(3-phenyl-2-propenoyl)-piperid
CAS number857064-38-1molecular formulaC17H14BrN3O
molecular weight356.22 g/molExact mass-
PSA65.800 Ųlogp3.400

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 0 shareMSDS