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P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt

Dangerous Goods

CAS number:102783-36-8    molecular formula:C20H28N10O19P4 · xNH3

overview

compound introduction

聚磷酸腺苷衍生物,存储在血小板,嗜铬细胞和神经元细胞的分泌颗粒中。已显示在体​​外起胰腺细胞次级信使,磷脂酶D刺激物,改变细胞内钙水平,一氧化氮释放诱导剂,5'-核苷酸酶激活剂和腺苷激酶活性抑制剂的作用。 用途 P1,P4-二(腺苷-5′)四磷酸铵盐已被用作nudix水解的底物。它还可用作ATP类似物以及切割因子II Im25亚基的nudix底物. A derivative of Diadenosine polyphosphate, which is stored in secretory granules of thrombocytes, chromaffin, and neuronal cells. Has been shown to function as a pancreatic cell secondary messenger, phospholipase D stimulator, change intracellular calcium levels, nitric oxide release inductor, 5′-nucleotidase activator and adenosine kinase activity inhibitor in vitro. Purpose P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt has been used as a substrate for nudix hydrolyse. It has also been used as a ATP analog and nudix substrate for cleavage factor II Im25 subunit.

Specs

Chinese aliasA(5′)p4(5′)A;四磷酸二腺苷 铵盐
English aliasA(5′)p4(5′)A, Diadenosine tetraphosphate ammonium salt
CAS number102783-36-8molecular formulaC20H28N10O19P4 · xNH3
molecular weight836.39 (free acid baExact mass≥95%
PSA-logp-

numbering system

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physicochemical properties

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Safety information

WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS:
AU7411600

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MSDS

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