说明: EB-3D 是一种有效的 choline kinase α (ChoKα) 的选择性抑制剂,对ChoKα1的IC50值为1 μM。EB-3D 可在白血病T细胞中诱导 AMPK-mTOR 通路失调和凋亡。 Information EB-3D EB-3D is a potent and selective inhibitor of choline kinase α (ChoKα) with IC50 of 1 μM for ChoKα1. EB-3D induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells. Targets ChoKα1 (Cell-free assay) 1 μM
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
EB-3D
Dangerous GoodsCAS number:1839150-63-8 molecular formula:C3OH36Br2N4O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Pyridinium,1,1'-[1,2-ethanediylbis(oxy-4,1-phenylenemethylene)]bis[4-(dimethylamino)-,bromide (1:2) | ||
| CAS number | 1839150-63-8 | molecular formula | C3OH36Br2N4O2 |
| molecular weight | 644.44 g/mol | Exact mass | 10mM in DMSO |
| PSA | 32.700 Ų | logp | 1.31 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS





