compound introduction
铁螯合剂Dp44mT是一种基于细胞可渗透的二-2-吡啶基硫代半碳酸盐（DpT）的三齿配体，在肿瘤细胞中表现出强效和选择性的抗增殖特性，对正常细胞的影响最小。铁螯合剂Dp44mT可以阻止M109肺癌在小鼠中的侵袭性生长，并且已被证明可以有效地动员细胞中的铁，并产生导致凋亡的ROS。 Product Describtion: Iron Chelator, Dp44mT is a cell-permeable di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand that displays potent and selective antiproliferative properties in neoplastic cells and minimally affects normal cells. Iron Chelator, Dp44mT prevents aggressive growth of M109 lung carcinoma in mice and has been shown to mobilize cellular iron effectively, and generate ROS leading to apoptosis. Product Application： Dp44mT may be used in cell signaling studies
